Endocrine Abstracts

Objective: The assessment of glycemic control and concentration of lipids in the blood in patients with type 1 diabetes mellitus (DM-1), depending on the presence of depression (DP).Methods: There were examined 163 patients with DM-1. To assess severity of DP there was used Hospital Anxiety and Depression Scale (HADS). There were determined the level of fasting blood glucose (BG), BG level in 2 hours after a meal, the average daily BG level for 3 days an...

The aim was to assess iodine status and thyroid structure changes in a cohort of patients with diabetes mellitus type 1 (DM1) at different stages of comorbid chronic kidney disease (CKD) after achievement of adequate iodine status in Belarus. We examined 62 patients (20m; 42f; age 42.1±12.07 years; BMI 26.14±5.27 kg/m2; duration of DM1 22.9±8.67 years; age at DM1 onset 19.89±12.72 years) at CKD stages 1, 2, 3, 5 (n=28; 21; 12; 1 respecti...

Introduction: Atherosclerotic complications are the leading causes of morbidity and mortality among patients with DT2.Aim: To investigate the possible role of dyslipidaemia, hypertension and chronic kidney disease (CKD) on the characteristics of carotid atherosclerosis (presence of plaque, carotid IMT and total plaque area) in patients with DT2.Material and methods: Patients aged 60–75 years with DT2 were included in this stud...

The aim of the work was to assess the dynamics of rates of carbohydrate metabolism in DM1 in young persons.Materials and methods: The study of daily dynamics of glucose was conducted by Continuous Glucose Monitoring System. For the analysis of continuous glycaemic curve there was conducted the computation of risk index (RI) of hypoglycemia and hyperglycemia during the study period.There were examined 162 patients with DM1. First gr...

Existing data on the anatomical state of the thyroid gland (ThG) in patients with chronic kidney disease (CKD) are contradictory.Objective: The aim was to analyze the anatomical features of the ThG and their correlation if it exists in patients with diabetes mellitus type 1 (T1DM) at different stages of comorbid CKD.Materials and methods: We recruited 53 patients (17 m; 36 f; age 43.7±11.3 years; BMI 25.8±5.0 kg/m2</...

The aim was to analyze the efficiency of various methods of examination to update the degree of diabetic nephropathy and to determine the optimal to predict the decline in renal function in patients with diabetes mellitus type 1 (T1DM).We examined 50 patients (17 m; 33 f; age 40.1±11.7 years; BMI 25.9±5.0 kg/m2; duration of T1DM 22.3±8.1 years; and age at T1DM onset 21.6±13.2 years) at chronic kidney disease (CKD) stages 1,...

Introduction: Belarus is included into an iodine deficiency region of Central Europe. Therefore the National program widely was introduced from 1999. This program included salt iodization with KIO3, using of iodizated salt in the food industry and in the field of catering.The purpose of the research is iodine status monitoring in the Republic of Belarus from 1999 to 2012.The investigations included determination of the t...

Implementation strategies for the elimination of iodine deficiency in the last 10 years in Belarus has achieved the WHO evaluation criteria. This was made possible by the universal use of iodized salt in food manufacturing, food service of all types and the availability of its free-trade network salt addition.The aim of this work was to study the iodine daily intake from food, as one of the measures to monitor iodine supply of the population.<p class...

To determine the relationship between indicators of inflammation and the blood redox status of type 2 diabetic (T2DM) patients with and without coronary heart disease (CHD).Forty four patients with T2DM and CHD (group 1), 67 patients with T2DM without cardiovascular complications (group 2), 89 healthy subjects (group 3) were included in this study. Serum concentrations of IL6 and IL8 were determined by ELISA using commercial kits. Concentrations of thiob...

Aim: The aim of this study was to investigate the role of C-reactive protein (CRP) in gestational diabetes mellitus.Material and methods: We studied 65 healthy pregnant women aged 29.75±5.59 years. All women referred for a 100–g oral glucose tolerance test following an abnormal result on a screening. The demographic data, waist circumference, height, and weight of the participants were recorded. Fasting levels of insulin, triglycerides (TG), CR...